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The Lit-Evi site is for showcasing all the main projects and developed/ing resources in the HZAU BioNLP lab. The resources mainly relate to literature evidence mined and curated by BioNLP methods and inferred knowledge by Bayesian frameworks.

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“Annotation of Genes with Alteration-Centric function changes”. — A customized corpus for mining functions caused by mutations.

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Literature-mined resources for regulatory events caused by genetic alterations. The extraction and curation of the event items is based on the in-house developed pipeline, GARE.

Cancer-Alterome

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This database includes 16,681 thousand of regulatory events records encompassing 21K genes, 157K genetic alterations and 154K downstream bio-concepts, extracted from 4,354K pan-cancer literature.

AD-Alterome

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A comprehensive database supporting the precise interpretation of the underlying pathological mechanisms of Alzheimer's disease. The web service provide convenient data queries, evidence displays, and result visualizations.

Rice-Alterome

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An ongoing project for rice annotation.

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We are building ontologies for concept normalization.

Rice Trait Ontology

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The rice trait ontology (RTO) project is to define rice-specific ontology concepts for rice traits and phenotypes.

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Various research strategies are used to extract, curate, and infer the knowledge bio-medicine. The main methods include BioNLP pipeline, Bayesian algorithms, and web-based data service.

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An evidence-augmented data fusion is run to support the driver gene discovery via interpretable literature evidence and omics data. Case studies in AD, lung cancer and breast cancer.

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As the title.

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A web service for querying the pathology networks with rich literature evidence in the Alzheimer's Disease context.

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An ongoing project for triplet evaluation in the context of Lacidipiscis.

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A "creepy" and symbolic version of BLCA event visualization.

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AD-LitMiner aims to present the most valuable AD literature statements and provides drug recommendations.

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AD-Data is a Chinese version of AD-LitMiner.

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Developing Team

HZAU BioNLP Lab

Affiliation: College of Informatics, Huazhong Agricultural University, Wuhan, Hubei, China

Lab PI: Jingbo Xia

All the contributors refer to above publications.